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Chinese scientists have achieved a significant medical milestone by successfully curing a long-term type 2 diabetes patient using a novel cell therapy. This breakthrough, reported on April 30 in the journal Cell Discovery, represents the world’s first successful use of stem cell-derived islet transplantation for diabetes.

The patient, a 59-year-old who had been managing diabetes for 25 years, received a transplant of pancreatic cells derived from his own stem cells in 2021 at Shanghai Changzheng Hospital. Prior to this, he had experienced a severe decline in pancreatic islet function following a kidney transplant in 2017, necessitating daily insulin injections.

The innovative treatment involved converting the patient’s blood cells into stem cells, which were then transformed into pancreatic islet cells. Within 11 weeks of the transplant, the patient no longer required external insulin, and within a year, he was able to discontinue oral diabetes medication altogether. Follow-up examinations indicated restored pancreatic and normal kidney functions, suggesting the patient had been cured of diabetes.

Diabetes remains a major global health challenge, affecting 422 million people worldwide, with current management primarily relying on insulin injections and other medications. This groundbreaking achievement in China, which comes after more than a decade of research, offers new hope for a potential cure.

Looking ahead, the FDA has approved a similar cell therapy developed by a Chicago-based startup for type 1 diabetes, showing a growing interest in this approach. However, Chinese researchers emphasize the need for further studies to confirm the long-term efficacy and broader applicability of their treatment. This pioneering work opens new avenues for diabetes therapy, potentially transforming the lives of millions affected by this chronic condition.

Scientists Cure Diabetes With Stem Cell Therapy In World First

, original content from Ubergizmo. Read our Copyrights and terms of use.

Chinese scientists have achieved a significant medical milestone by successfully curing a long-term type 2 diabetes patient using a novel cell therapy. This breakthrough, reported on April 30 in the journal Cell Discovery, represents the world’s first successful use of stem cell-derived islet transplantation for diabetes.

The patient, a 59-year-old who had been managing diabetes for 25 years, received a transplant of pancreatic cells derived from his own stem cells in 2021 at Shanghai Changzheng Hospital. Prior to this, he had experienced a severe decline in pancreatic islet function following a kidney transplant in 2017, necessitating daily insulin injections.

The innovative treatment involved converting the patient’s blood cells into stem cells, which were then transformed into pancreatic islet cells. Within 11 weeks of the transplant, the patient no longer required external insulin, and within a year, he was able to discontinue oral diabetes medication altogether. Follow-up examinations indicated restored pancreatic and normal kidney functions, suggesting the patient had been cured of diabetes.

Diabetes remains a major global health challenge, affecting 422 million people worldwide, with current management primarily relying on insulin injections and other medications. This groundbreaking achievement in China, which comes after more than a decade of research, offers new hope for a potential cure.

Looking ahead, the FDA has approved a similar cell therapy developed by a Chicago-based startup for type 1 diabetes, showing a growing interest in this approach. However, Chinese researchers emphasize the need for further studies to confirm the long-term efficacy and broader applicability of their treatment. This pioneering work opens new avenues for diabetes therapy, potentially transforming the lives of millions affected by this chronic condition.

Scientists Cure Diabetes With Stem Cell Therapy In World First

, original content from Ubergizmo. Read our Copyrights and terms of use.

Newly proposed Congressional legislation would require the US to conduct security reviews for connected vehicles built by automakers from China and “other countries of concern.” Rep. Elissa Slotkin (D-MI), a former CIA analyst and Pentagon official who has championed the issue, introduced the bill on Wednesday.

If passed by Congress (a tall order these days), the Connected Vehicle National Security Review Act would establish a formal review process for connected autos from Chinese companies. It would also allow the Department of Commerce to limit or ban these cars and other vehicles before they reach US consumers.

“Today’s vehicles are more sophisticated than ever, carrying cameras, radars and other sophisticated sensors, plus the ability to process, transmit and store the data they gather from the United States,” said Slotkin. “If allowed into our markets, Chinese connected vehicles offer the Chinese government a treasure trove of valuable intelligence on the United States, including the potential to collect information on our military bases, critical infrastructure like the power grid and traffic systems, and even locate specific U.S leaders should they so choose.”

Rep. Elissa Slotkin

In a speech on the House floor earlier this month, Slotkin noted that Chinese EVs, often sold much cheaper than their US and European counterparts, could quickly gain a significant share of the American market. She cited how Chinese vehicles, first sold in Europe in 2019, now make up almost a quarter of its market. The representative also recently pushed Secretary of the Army Christine Wormuth and Secretary of Defense Lloyd Austin on the security gap.

Alternatively (and perhaps ideally), legislators could pass a comprehensive data privacy law rather than dealing with these issues piecemeal.

The bill’s introduction follows the Biden Administration’s quadrupling of import tariffs on Chinese EVs. The White House’s new EV levies grew from 25 percent to 100 percent, following China’s EV exports rising 70 percent between 2022 and 2023.

In February, the White House also ordered the Department of Commerce to investigate the risks of connected vehicles from China and other adversaries. However, that action was conducted through an executive order and could be undone by future administrations. Slotkin’s legislation would close those loopholes if it makes it through Congress — rarely a safe bet in today’s highly obstructed and contentious political environment.

This article originally appeared on Engadget at https://www.engadget.com/us-house-bill-would-require-national-security-reviews-on-connected-vehicles-from-china-211505179.html?src=rss

Elon Musk has been talking with Donald Trump “several times a month,” about a wide range of topics, according to a new report from the Wall Street Journal. And while Musk has denied rumors that he might donate money to the former president, the new reporting indicates Musk is working behind the scenes to make sure his…

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In a recent success story, hardware hacker Joe Grand helped “Michael,” a European cryptocurrency owner, recover $3 million worth of bitcoin after an 11-year-old password was cracked. Michael had stored his 43.6 BTC in a password-protected digital wallet, using a password generated by the RoboForm password manager; He encrypted this password with TrueCrypt, but when the file became corrupted, he lost access to it.

Initially, Grand turned down Michael’s request for help, but he reconsidered last year. Michael had contacted various cryptography experts, all of whom believed recovering the password was impossible. Grand, who is known for his expertise in hardware hacking, had previously helped recover $2 million in cryptocurrency from a Trezor wallet using advanced techniques — However, Michael’s case involved a software-based wallet, making Grand’s usual hardware skills less applicable.

Grand considered brute-forcing the password, but this approach was impractical given the complexity and length of the password; He also pondered the possibility of a flaw in the RoboForm password manager that might allow for easier guessing, but he doubted such a flaw existed — Turns out, it did! The specific version of the wallet that Michael installed had “a limitation” in its randomization feature for generating the password.

Teaming up with his friend Bruno in Germany, who also specializes in hacking digital wallets, Grand eventually agreed to tackle the problem. Despite the initial doubts and the challenges posed by the software-based encryption, their combined expertise and a stroke of luck led to the successful recovery of Michael’s bitcoin.

Hacker Recovers $3M In Bitcoin After Cracking 11-Year-Old Password

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