Engineers say the final images produced by the new system contain 100 times more information than those produced by conventional microscope platforms.
(Credit: Yan Liang and Guoan Zheng)
Ah, physics. The cold, hard reality of how things work so often gets in the way of how we would prefer them to work.
But when it comes to the field of microscopy, which has been held back by the physical limitations of optical lenses, a group of engineers at Caltech say they’ve been able to use a computational approach to bypass these limitations — and that the final images produced using their new system contain 100 times more information. What’s more, the system costs just $200 to implement with a conventional microscope.
In a nutshell, the limitations of optical lenses have forced researchers to pick and choose between a system that gives them high resolution over a small field of view or low resolution over a wider field of view. See a little bit clearly or a lot coarsely.
“We found a way to actually have the best of both worlds,” Guoan Zheng, lead author of the new paper in Nature Photonics, said in a school news release. “The optical performance of the objective lens is rendered almost irrelevant, as we can impr… [Read more]
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