Variants In RORA Gene Linked To PTSD, Among Other Stress Disorders

RORA, overexpressed and underexpressed

The retinoic acid receptor-related orphan receptor alpha, RORA for
short, is a gene that ordinarily protects our fragile cells from stress,
but scientific findings in the last few years have shown that the RORA
gene often shuts down when certain other cells destabilize them.  This
study, conducted by Boston University School of Medicine and the VA
Boston Healthcare System, finds yet another psychiatric disorder, post
traumatic stress disorder (PTSD), linked to a breakdown or ‘risk variant’
of the RORA gene.

 


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