NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles

We’re guessing that most Wolfpackers in the greater Raleigh area are in full-on tailgate mode right now, but aside from laying a beating on the Seminoles this evening, NC State faithful are also trumpeting a new DNA discovery that could one day make it easy to get vital drugs to hard-to-reach places within you. Researchers from the university have purportedly discovered the ‘Goldilocks’ of DNA self-assembly, which holds promise for technologies ranging from drug delivery to molecular sensors. The concept, known as DNA-assisted self-assembly, has been vastly improved by using “computer simulations of DNA strands to identify the optimal length of a DNA strand for self-assembly.” You see, perfection occurs when strands aren’t long enough to intertwine with each other, yet not short enough to simply fold over on each other. We know, it’s a lot to wrap your brain around with half a hot dog shoved in your mouth, but hit the video after the break for a… shall we say, more visual explanation.

Continue reading NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles

NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles originally appeared on Engadget on Thu, 28 Oct 2010 15:35:00 EDT. Please see our terms for use of feeds.

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Eizo rolls out 17-inch FlexScan T1751 multitouch monitor

Eizo may not be aiming this one directly at average consumers, but there’s nothing stopping you from picking up its new 17-inch FlexScan T1751 monitor to make your industrial-style mutlitouch dreams come true. As you can sort of see above, this one can either be used upright or titled nearly flat, and it packs a non-widescreen, 5:4 aspect ratio — albeit with a slightly disappointing 1,280 x 1,024 resolution. The monitor will work with a touch pen and gloved hands, however, and you’ll get a decent 178 degree viewing angle, along with a 1,500:1 contrast ratio, a pair of built-in 0.5W speakers, a headphone jack and, true to its industrial nature, a non-scratch surface made of reinforced glass. No official word on a price or release date, unfortunately — Eizo is simply telling folks to check with their local distributor for details.

Continue reading Eizo rolls out 17-inch FlexScan T1751 multitouch monitor

Eizo rolls out 17-inch FlexScan T1751 multitouch monitor originally appeared on Engadget on Sat, 16 Oct 2010 00:40:00 EDT. Please see our terms for use of feeds.

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Sofie surgical robot gives haptic feedback for a more humane touch

Surgical procedures assisted by robots are nothing new — they can be more precise and less invasive — and now it looks like a new upgrade could make them even better. The main drawback of a surgical robot is that the human surgeon performing the operation gets no tactile feedback, but that’s not the case with Sofie. Sofie, a joystick controlled robot gives haptic feedback to the surgeon by adjusting the resistance the controls give to indicate how much pressure is being exerted, surely a welcome addition to bots of this kind. This robot is also more compact than many earlier bots of this kind, and its creators are now looking to bring it into production, with a goal of it coming to the market in about five years.

Sofie surgical robot gives haptic feedback for a more humane touch originally appeared on Engadget on Mon, 11 Oct 2010 23:13:00 EDT. Please see our terms for use of feeds.

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Murata’s fatigue sensor demoed, coming soon to mobiles and handhelds near you

Need further confirmation that an IV drip of 5-Hour Energy is what your body really needs? Look no further than Murata’s newfangled fatigue sensor. Demonstrated at CEATEC in front of thousands of jetlagged Americans, Europeans, Easter Islanders and Samoans, this compact device is built by “integrating a photoplethysmographic sensor, which measures a pulse and a blood oxygen saturation level, and electrodes that measure electrocardiogram (ECG).” We’re told that the unit measures a fatigue degree (reported on a 1 to 100 scale) based on the “pulse, blood oxygen saturation level and electrocardiogram measured by the sensing parts,” and while we’re guessing the prototype will have to shrink significantly before it happens, the company seems focused on cramming this thing into cellphones and portable game consoles of the future.You know — so Nintendo actually can know when you need to lay down the gaming and step outside for a bit.

Murata’s fatigue sensor demoed, coming soon to mobiles and handhelds near you originally appeared on Engadget on Mon, 11 Oct 2010 16:51:00 EDT. Please see our terms for use of feeds.

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Wireless body area network allows your body to send status updates to your cellphone

Dutch researchers recently demonstrated a new type of wireless body area network, or BAN for short. A BAN essentially gives the human body its own IP address, and the new techniques demonstrated at IMEC based in Eindhoven incorporate a dongle that plugs into the SD card slot of a cellphone, enabling the streaming of data from the sensors to the cellphone in real time. The demonstrated software, which runs Android OS and uses the nRF24L01+ radio wireless standard rather than Bluetooth. So what does this mean for the future of medicine? Well, with just a few EKG-like sensors, people with medical conditions such as heart problems, or athletes in training, will be able to monitor their own body on their cellphones. The technology is still in the demo phase, but it’s one we look forward to seeing in practice. Video is below.

Continue reading Wireless body area network allows your body to send status updates to your cellphone

Wireless body area network allows your body to send status updates to your cellphone originally appeared on Engadget on Sun, 10 Oct 2010 03:03:00 EDT. Please see our terms for use of feeds.

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Berkeley Bionics reveals eLEGS exoskeleton, aims to help paraplegics walk in 2011 (update: eyes-on and video)

Wondering where you’ve heard of Berkeley Bionics before? These are the same whiz-kids who produced the HULC exoskeleton in mid-2008, and now they’re back with a far more ambitious effort. Announced just moments ago in San Francisco, the eLEGS exoskeleton is a bionic device engineered to help paraplegics stand up and walk on their own. It’s hailed as a “wearable, artificially intelligent, bionic device,” and it’s expected to help out within the hospital, at home and elsewhere in this wild, wild place we call Earth. Initially, the device will be offered to rehabilitation centers for use under medical supervision, and can be adjusted to fit most people between 5’2″ and 6’4″ (and weighing 220 pounds or less) in a matter of minutes. We’re told that the device provides “unprecedented knee flexion,” and it’s also fairly quiet in operation; under ideal circumstances, speeds of up to 2MPH can be attained, and it employs a gesture-based human-machine interface that relies on legions of sensors to determine a user’s intentions and act accordingly. Clinical trials are going on as we speak about to begin, and there’s a limited release planned for the second half of 2011. We’re still waiting to hear back on a price, so keep it locked for more as we get it live from the event.

Update: We just got to see the eLEGS walk across stage, and you’ll find a gallery full of close-up pics immediately below. We also spoke to Berkeley Bionics CEO Eythor Bender, who detailed the system a bit more — it’s presently made of steel and carbon fiber with lithium-ion battery packs, weighs 45 pounds, and has enough juice to run for six hours of continuous walking. While he wouldn’t give us an exact price, he said they’re shooting for $100,000, and will be “very competitive” with other devices on the market. Following clinical trials, the exoskeleton will be available to select medical centers in July or August, though Bender also said the company’s also working on a streamlined commercial version for all-day use, tentatively slated for 2013.

Continue reading Berkeley Bionics reveals eLEGS exoskeleton, aims to help paraplegics walk in 2011 (update: eyes-on and video)

Berkeley Bionics reveals eLEGS exoskeleton, aims to help paraplegics walk in 2011 (update: eyes-on and video) originally appeared on Engadget on Thu, 07 Oct 2010 14:44:00 EDT. Please see our terms for use of feeds.

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Young Boy Becomes First Human to Live With a Permanent "Robot Heart" [Medicine]

Until now, all other artificial heart transplants were just temporary relief. A 15 year old boy from Italy became the first person to receive a permanent artificial heart, due to the Duchenne syndrome which was wasting his muscles away. More »

Neurosurgeons use MRI-guided lasers to ‘cook’ brain tumors

In the seemingly perpetual battle to rid this planet of cancer, a team of neurosurgeons from Washington University are using a new MRI-guided high-intensity laser probe to “cook” brain tumors that would otherwise be completely inoperable. According to Dr. Eric C. Leuthardt, this procedure “offers hope to certain patients who had few or no options before,” with the laser baking the cancer cells deep within the brain while leaving the good tissue around it unmarred. The best part, however, is that this is already moving beyond the laboratory, with a pair of doctors at Barnes-Jewish Hospital using it successfully on a patient last month. Regrettably, just three hospitals at the moment are equipped with the Monteris AutoLITT device, but if we know anything about anything related to lasers, it’ll be everywhere in no time flat.

Neurosurgeons use MRI-guided lasers to ‘cook’ brain tumors originally appeared on Engadget on Sat, 02 Oct 2010 23:59:00 EDT. Please see our terms for use of feeds.

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Researchers develop wireless sensor network to measure physical activity

Wearable sensors that monitor physical activity are hardly anything new, but some researchers from MSU’s Department of Kinesiology are taking the idea quite a bit farther with their latest project. They’ve developed a new system that employs a network of sensors that not only track movement, but can monitor things like tilt, posture and the proximity of limbs to each other. That, the researchers say, allows them to detect different types of activity, and more accurately measure the energy expended on them. Of course, it is still just a prototype, but it’ll apparently soon be put to the test by some graduate students, and there’s plenty of backing behind it — the project is being funded two-year, $411,000 grant from the National Institutes of Health.

Researchers develop wireless sensor network to measure physical activity originally appeared on Engadget on Sat, 18 Sep 2010 21:04:00 EDT. Please see our terms for use of feeds.

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Perform CPR Correctly with PocketCPR

zoll-pocket-cpr.jpg

Be a hero and save a life with Zoll’s PocktCPR. Intended to be used by people already trained in CPR, it reminds the user what to do and gives feedback on whether it’s being done correctly.

Performing CPR incorrectly may harm the victim. For that reason, many bystanders are often reluctant to step in and be the hero. PocketCPR issues step-by-step audio and visual instructions on what to do.

By placing the PocketCPR on the victim’s chest before beginning CPR chest compressions, the device can give real-time verbal feedback and visual indicators to ensure it is being done correctly. If it’s done correctly, PocketCPR will say, “Good compressions,” and flash four LED lights. Otherwise, it will say “Push harder,” and flash just one LED.

The accelerometer inside the device measures the rate and depth of chest compressions and an audible metronome helps maintain the rate and rhythm.

Before beginning the compressions, the instructions remind you to calm down, check for the victim’s responsiveness and call for help.

There is a silent mode to suppress audible feedack. The lights continue to flash in silent mode.

The battery lasts about 12 hours before needing to be changed.

PocketCPR is approved by the FDA and is available for $149 online. Disposable sanitary slip-covers are sold separately. An app is also available to transform the iPhone into a PocketCPR. The app is not cleared by the FDA and should be used for training purposes only.