NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles

We’re guessing that most Wolfpackers in the greater Raleigh area are in full-on tailgate mode right now, but aside from laying a beating on the Seminoles this evening, NC State faithful are also trumpeting a new DNA discovery that could one day make it easy to get vital drugs to hard-to-reach places within you. Researchers from the university have purportedly discovered the ‘Goldilocks’ of DNA self-assembly, which holds promise for technologies ranging from drug delivery to molecular sensors. The concept, known as DNA-assisted self-assembly, has been vastly improved by using “computer simulations of DNA strands to identify the optimal length of a DNA strand for self-assembly.” You see, perfection occurs when strands aren’t long enough to intertwine with each other, yet not short enough to simply fold over on each other. We know, it’s a lot to wrap your brain around with half a hot dog shoved in your mouth, but hit the video after the break for a… shall we say, more visual explanation.

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NC State gurus find ‘Goldilocks’ of DNA self-assembly, look to improve drug-delivery vehicles originally appeared on Engadget on Thu, 28 Oct 2010 15:35:00 EDT. Please see our terms for use of feeds.

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Liquavista displays get flexible, ‘unbreakable,’ still rather theoretical (video)

Liquavista displays get flexible, 'unbreakable,' still rather theoretical (video)

The next generation of display technology is still that, next, but despite being a future away it continues to get better. Liquavista keeps wowing us with various demonstrations of its electrowetting technology offering full color, high refresh rates, visibility in all lighting conditions, and low power consumption to boot. Now they’re bendy too, with the company releasing footage of a prototype that’s flexible. It’s also said to be “unbreakable,” demonstrated by a person wearing latex gloves gently tapping on the screen — because, you know, that’s about as tough as it gets outside of the lab. Video is after the break, along with full PR, but in neither will you find any hope of seeing this tech for real before the second half of next year.

Continue reading Liquavista displays get flexible, ‘unbreakable,’ still rather theoretical (video)

Liquavista displays get flexible, ‘unbreakable,’ still rather theoretical (video) originally appeared on Engadget on Thu, 28 Oct 2010 08:19:00 EDT. Please see our terms for use of feeds.

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New Science: You Have Taste Receptors in Your Lungs

lung_faces.gifThe human body is weird. A U.K. man recently underwent surgery to remove a tooth growing in his ear. And who could forget the tale of the newborn baby who had a fully-formed foot growing in its brain!? Crazy, right? But, as it turns out, it’s not just the occasional misplaced tooth or aberrant foot, everybody is a freak. According to a recent discovery: we can taste with our lungs.

Researchers at the Maryland School of Medicine recently published their findings regarding a strange discovery: we all have bitter taste receptors growing in our bronchial tissue. The team came upon the find accidentally while pursuing unrelated research into muscle receptors in the lungs.

The bitter taste receptors are the exact same kind located on the tongue, but with two differences: unlike on the tongue, the lung receptors are not bunched into taste buds, and they don’t seem to communicate directly to the brain.

However, these findings may have very real implications for asthma patients. Bitter taste receptors tend to tighten or constrict muscle tissue around them. These lung receptors may exist for a very practical reason: to prevent bitter-tasting plant based poisons from entering the body. But in asthma patients, these reactors may become stimulated by man-made chemicals that they mistake for naturally-occurring plant toxins.

Just nuts.

Japanese Table-top Gadget turns Plastic to Oil


There are millions of pounds of plastic in landfills around the country and floating in that big huge garbage patch in the middle of the Pacific Ocean – you know, the one the size of Texas – and only a fraction of the plastic used in the United States alone actually gets recycled. Thanks to one Japanese inventor and engineer, the table-top Blest Machine (Japanese) essentially takes plastic, melts it down, separates the gases and condensation from the melted plastic, and produces burnable fuel oil at the end. He says about two pounds of plastic will net you a quart of oil, and the oil can even be further refined into other petroleum-based products like gasoline.

What’s the catch? The second law of thermodynamics says no system is perfect, so before anyone thinks this is a perpetual motion scam, note that you actually have to dump energy into the Blest Machine to melt down the plastic, process it, and produce the oil on the other end.

This isn’t free energy by any stretch, but that’s not the point: the $9,500 table-top gadget isn’t designed to be an energy producer, it’s meant to give people and municipalities a way to use electricity (which can be produced using sustainable means) to get rid of plastic waste and turn it into something that’s useful today, like oil. Right now the Blest Machine is only available in Japan, but expect to see it pop up around the globe soon.

[via DVice]

Scientists Attempt to Prove Universe is Actually a Cartoon

across-the-universe.jpg

3-D is the hottest new trend in movies. But it’s all just filmmakers punking the human brain into perceiving depth in a two-dimensional image. And, according to some theoretical physicists, this may be how the Universe works. Depth is all an illusion of time. The Big Bang never occurred. And you, your family, your pets, every monkey that ever existed, the entire cast of The Jersey Shore, and the starting line-up of the 2010 All-Star game are all two-dimensional holograms. The Universe is a big flat cartoon.

So goes one theory.

The theory of a Holographic Universe has floated around for sometime. But it’s never had any hard data to back it up–it was just an explanation that nicely tied up mathematical loose-ends about black holes and gravity on a chalk board.

However some evidence for the unreality of reality may have showed up last year. The GEO600 is an internationally-collaborative experiment based in Germany that is attempting to detect and measure theoretical gravitational waves–or minute ripples in the fabric space-time. However, the experiment just keeps running into low levels of “noise.” The GEO600 team still plans to continue searching through the noise to detect these theoretical gravitational waves.

But Craig Hogan, a particle astrophysicist with the US Government-sponsored high-energy physics research lab Fermilab thinks the GEO600 team found exactly what they were looking for. Hogan sees this barrier of noise as a blurring or pixelating effect from zooming in too far. He theorizes that this is exactly what one would expect to happen if the Universe were a two-dimensional hologram. And now he and his team want to prove it.

Hogan is overseeing a super-sensitive holometer being developed at Fermilab. The holomter is almost like a super precise clock that will be able to measure the inherent fuzziness of space-time, and may give a clue to it’s true form. Hogan and his team are building two devices to confirm each other’s work. They hope to start collecting data next year.

via Symmetry Magazine

A Solar Power Breakthrough, Courtesy of the Guy Who Invented the Super Soaker [Energy]

Lonnie Johnson did risk assessment for the Atlantis space shuttle. He helped get the B-2 stealth bomber off the ground. He gave us the Super Soaker. And now, with his latest invention, he might just make solar power viable. More »

Honeybee Death Mystery Solved [Bees]

Honeybees have been dropping like flies for the past half decade, and the mass-death has been confusing the hell out of scientists. Was it because of cell phones? No. More »

The Rocket Project Documentary Hits the Science Channel

Rocket Project - Students

Back in July, a team of high school students gathered on the dusty flats of the Black Rock Desert in northern Nevada with a single purpose: to launch a 29-foot rocket into orbit using some rocketry training, their knowledge of physics, and a couple of Sony laptops powered by Intel Core i5 and Core i7 processors. The event was the culmination of The Rocket Project, and after several delays and weather mishaps, the students finally managed to launch their rocket into orbit successfully.

Following the students on that journey were a handful of documentary filmmakers who released short episodes of the students trials and successes, and now a complete half-hour Rocket Project Documentary will air on The Science Channel tonight at 9:00pm Eastern (check your local listings for additional airings.) If you miss the half-hour documentary though, the shorter Web episodes that follow the months-long story of the launch are still available at The Rocket Project Web site.
 

In High School Chem Labs, Every Cameraphone Can Be a Spectrometer

University of Illinois chemistry professor Alexander Scheeline has developed software that turns a camera phone, an LED, and a few other cheap tools into a spectrometer. Armed with these, he thinks we can bring high-end analytic tools to high school chemistry labs all over the world.

“The potential is here to make analytical chemistry a subject for the masses rather than something that is only done by specialists,” Scheeline said. “There’s no doubt that getting the cost of equipment down to the point where more people can afford them in the education system is a boon for everybody.”

Purpose-built spectrophotometers are essential tools in analytic chemistry. By measuring the electromagnetic spectrum a substance absorbs or emits, you can determine its molecular composition. They’re also expensive, which is why they’ve generally been confined to universities. Scheeline has already brought his cellphone spectrometers to high schools in Atlanta and Hanoi. Other high-school chemistry and physics teachers doing professional development at Illinois have also brought Scheeline’s tools to their classrooms.

Initially, Scheeline hadn’t been looking for ways for students to use their phones in class. Instead, he wanted students to build their own spectrophotometry tool, to better understand their instruments and their limitations. Putting together the LED as a light source, diffraction gratings and cuvettes were easy; finding a small sensor to capture the light was hard.

“All of a sudden this light bulb went off in my head: a photodetector that everybody already has! Almost everybody has a cellphone, and almost all phones have a camera,“ Scheeline said. “I realized, if you can get the picture into the computer, it’s only software that keeps you from building a cheap spectrophotometer.”

Scheeline with the analysis software he’s developed for the cell-phone spectrometer.

Scheeline wrote a Windows desktop program to analyze the students’ JPEG files from their phones. One advantage of this approach over developing a smartphone application to do the analysis directly: Because the phones are used only to take the photographs, it doesn’t matter what operating system a student’s phone is running.

Scheeline then published his source code, a compiled executable application and the cellphone spectrometer instructions for anyone to download from the Analytical Sciences Digital Library. He also published an article on the device and its potential in chemistry education in the academic journal Applied Spectroscopy.

“Science is basically about using your senses to see things – it’s just that we’ve got so much technology that now it’s all hidden,” Scheeline said. “The student gets the impression that a measurement is something that goes on inside a box and it’s completely inaccessible, not understandable – the purview of expert engineers.”

“In order to get across the idea, ‘I can do it, and I can see it, and I can understand it,’ they’ve got to build the instrument themselves,” he added.

Can you analyze me now? Cell phones bring spectroscopy to the classroom [University of Illinois]

All images by L. Brian Stauffer via news.illinois.edu

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Nobel Prize in Chemistry Awarded for Carbon Bonds

nobel-chemistry-2010.jpg

2010 is shaping up to be a big year for carbon at the Nobel Prize committee. After awarding the prize in physics to two Russian-born scientists for their research on the ultra-thin carbon construction known as Graphene, the committee has given the prize in chemistry to three professors who developed a tool for create carbon-carbon bonds.

Two of the professors are U.S.-based–Richard Heck of the University of Delaware and Ichi Negishi of Perdue. The third, Akira Suzuki, is a professor at Japan’s Hokkaido University.

The committee had the following to say about the trio’s work,

This chemical tool has vastly improved the possibilities for chemists to create sophisticated chemicals, for example carbon-based molecules as complex as those created by nature itself.

The tool is known as palladium-catalyzed cross-coupling–I’m sure it’ll get a slicker name, once Hollywood gets its hands on it. Palladium-catalyzed cross-coupling has a wide range of potential uses in fields like agriculture, pharmaceuticals, and electronics.

“The key word here is versatility,” Negishi told CNN. “One of our dreams is to be able to synthesize any organic compounds of importance, whether it is medicinally important compounds … or important from the point of view of material science. And we believe that our technology or our chemistry will be applicable to a very wide range of compounds, without knowing what they might be.”